Pharmaceutical Excipient


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There has been a consistent growth in the consumption of sodium based medicines which has led to an increase in demand for sodium bicarbonate in pharmaceutical formulations. These formulations require high levels of purity; therefore a pharma grade sodium bicarbonate is a safe choice for making formulations.

Medikarb from Tata Chemicals is India’s first pharma grade sodium bicarbonate. As a part of the $100bn Tata conglomerate, Tata Chemicals is a key manufacturer of alkali chemicals. Medikarb delivers quality and meets the requirement of Indian and global pharmaceutical manufacturers.

What are the uses of Medikarb in pharmaceutical formulations?

  • Used as an active pharmaceutical ingredient
  • As a pharmaceutical excipient
  • Used as a buffering agent in effervescent salts and antacids
  • Used as excipient in tablets

Why is Medikarb superior in quality? Read the table to find out.

  • Medikarb is manufactured in a state of the art FDA licensed facility
  • Highly mechanised manufacturing process and designed in line with GMP principles
  • Quality is guided by an end-to-end Tata QMS (Quality Management System)
  • Product conforming to Indian Pharmacoepia specifications
PARAMETERS ASSURED SPECIFICATIONS TYPICAL RESULTS
Sodium Bicarbonate Assay (as NaHCO3) 99 to 101 % by mass 99.5 ± 0.2 % by mass
pH of freshly prepared 5% solution 8.6 max 8.0 to 8.2
Chlorides (as Cl) 200 PPM max Less than 100 PPM
Sulphate (as SO4) 150 PPM max Less than 100 PPM
Iron (as Fe) 20 PPM max Less than 10 PPM
Carbonate Passes I.P. test Complies
Calcium (as Ca) Passes I.P. test Complies
Heavy metals (as Pb) 5 PPM max Less than 4 PPM
Arsenic (as As) 2 PPM max Less than 2 PPM

 

Description A white, crystalline powder or small opaque monoclinic crystals. It gradually forms sodium carbonate on heating in the dry state or in solution.
Solubility Freely soluble in water, practically insoluble in ethanol (95%). Freely soluble in water, practically insoluble in ethanol (95%).
Identification Test A,B & C should be comply [as per I.P.] Complies
Appearance of solution Solution A should be clear & colourless Solution A is clear & colourless
Particle size distribution   3% max retention on 40 ASTM mesh
Moisture   **Optional**
Black particle test   **Optional**
Microbiological tests   **Optional**
Magnesium (as Mg)   **Optional**
Aluminum (as Al)   **Optional**

Services offered by Tata Chemicals team to Medikarb buyers:

  • Premium sales support through dedicated distributors in pharma clusters
  • Technical sales support through in-house R&D and technical service teams
  • Small order lots and express deliveries available

For orders & enquiries, call us on +91-20-6607-5100

Medikarb price announcement Download Medikarb brochure

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